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. 2021 May 10;11:9823. doi: 10.1038/s41598-021-89168-6

Table 3.

Participant demographic and environmental characteristics.

PD group as a whole HS group as a whole p values
Number 86 83
Male/female 56/30 38/45 0.018
Age (yrs, mean ± SD) 65.7 ± 0.94 63.7 ± 1.16 0.10
BMI (mean ± SD) 25.32 ± 4.17 25.04 ± 3.34 0.99
Coffee cups/day (mean ± SD) 2.53 ± 0.15 2.66 ± 0.15 0.53
Caffeine intake, mg/day (mean ± SD) 211.69 ± 107.58 217.81 ± 110.18 0.77
Tobacco smoking (n) 9 6 0.34
Early PD Age-matched HS p values
Number 39 39
Male/female 15:24 25:14  < 0.01
Age (yrs, mean ± SD) 61.1 ± 7.33 59.6 ± 7.17 0.16
BMI (mean ± SD) 24.33 ± 4.06 24.45 ± 3.20; 0.51
Coffee cups/day (mean ± SD) 2.79 ± 1.34 2.64 ± 1.44 0.72
Caffeine intake, mg/day (mean ± SD) 234.10 ± 104.60 211.89 ± 113.08 0.46
Tobacco smoking 4 3 0.89
Moderate/advanced PD Age-matched HS p values
Number 47 44
Male/female 29:18 24:20 0.66
Age (yrs, mean ± SD) 69.71 ± 10.59 67.75 ± 8.00 0.13
BMI (mean ± SD) 26.31 ± 4.11 25.50 ± 3.44 0.47
Coffee cups/day (mean ± SD) 2.32 ± 1.33 2.69 ± 1.29 0.23
Caffeine intake, mg/day (mean ± SD) 193.09 ± 107.55 223.84 ± 108.72 0.25
Tobacco smoking 5 3 0.46