Skip to main content
. 2021 Apr 27;12:607785. doi: 10.3389/fphar.2021.607785

FIGURE 5.

FIGURE 5

The aFGF–NP + CPMBs combined with UTMD inhibited cardiomyocyte apoptosis in DOX–HF rats. (A): Representative photos of TUNEL staining in each group(400x); (B): Quantitative analysis of the apoptotic cells. The protein expression of Bax and Bcl–2 in myocardial tissue was detected by Western blot. (C, D) Representative photos of Western blot; (E, F) Statistical analysis of the protein expression of Bax and Bcl–2. All data are expressed as mean ± SEM. *p < 0.05 vs. Control group; +p < 0.05 vs. DOX–HF group; #p < 0.05 vs. aFGF–NP + UTMD group. aFGF, acidic fibroblast growth factor; NP, nanoparticles; CPMBs, cationic lipid microbubbles; UTMD, ultrasound targeted microbubble destruction; DOX, doxorubicin; HF, heart failure. Prevention the decreation of myocardial capillary density in DOX–HF.