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. 2021 May 3;36(18):e132. doi: 10.3346/jkms.2021.36.e132

Table 3. Risk factors associated with in-hospital death and severe cases requiring oxygen therapy.

Variables In-hospital deatha Oxygen therapyb
Univariate Multivariate Univariate Multivariate
OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
Sex
Male vs. female 1.6 (1.2–2.1) 2.3 (1.6–3.1) 1.3 (1.1–1.5) 1.6 (1.3–1.9)
Age (yr)
60–69 vs. 0–59 7.0 (3.8–12.8) 4.4 (2.3–8.3) 4.3 (3.4–5.3) 3.2 (2.5–4.0)
70–79 vs. 0–59 26.8 (15.5–46.1) 16.3 (9.0–29.5) 9.5 (7.6–11.9) 6.8 (5.2–8.8)
≥ 80 vs. 0–59 110.5 (65.1–187.6) 79.4 (43.2–146.0) 22.5 (17.3–29.4) 18.4 (13.4–25.3)
No. of comorbidities
1–2 vs. 0 10.6 (7.1–16.0) 2.8 (1.8–4.5) 4.6 (3.9–5.5) 2.1 (1.8–2.9)
≥ 3 vs. 0 43.5 (26.8–70.4) 5.5 (3.1–9.8) 13.5 (9.9–18.4) 3.6 (1.7–2.6)
Symptoms on admission
Yes vs. no 1.4 (1.0–2.0) 1.7 (1.1–2.6) 2.1 (1.7–2.6) 2.3 (1.8–2.9)
Systolic BP (mmHg)
≥ 120 vs. < 120 0.9 (0.7–1.3) 0.5 (0.3–0.8) 1.2 (1.0–1.5) 0.9 (0.7–1.1)
Diastolic BP (mmHg)
≥ 80 vs. < 80 0.7 (0.5–0.9) 1.1 (0.7–1.6) 0.8 (0.7–0.9) 0.8 (0.7–1.0)
Heart rate (bpm)
≥ 120 vs. < 120 4.6 (2.8–7.5) 5.6 (3.0–10.5) 2.7 (1.8–4.0) 2.2 (1.4–3.5)
Body temperature (°C)
≥ 37.5 vs. < 37.5 2.2 (1.7–3.0) 2.5 (1.7–3.7) 2.9 (2.4–3.4) 2.9 (2.4–3.6)

OR = odds ratio, CI = confidence interval, BP = blood pressure.

aC-statistics = 0.93, P value for the Hosmer-Lemeshow test = 0.768; bLogistic regression models (univariate and multivariate) with maximum disease severity level 3 or higher as the dependent variable (C-statistics = 0.83, P value for Hosmer-Lemeshow test = 0.008).