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. 2021 May 1;6(12):4402–4414. doi: 10.1016/j.bioactmat.2021.04.027

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© 2021 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 4 — Characterization of biomimetic nanosuspensions. (A) SEM of paclitaxel powder. The drug had a crystalline structure. Cell membrane vesicles (B), (PTX)NS(C) and ^DWSW-CCM-(PTX)NS(D) transmission electron microscopy images. The drug nanosuspension was approximately spherical and had a core-shell structure after being wrapped by the cancer cell membranes. (E) The membrane protein of the biomimetic nanosuspensions was determined by SDS-PAGE. WB measurement and relative gray value of membrane-specific proteins CD47 (F and H) and CD44 (G and I).