TABLE 4.

Multivariate analysis of the effects of treatment, trimester of maternal infection, and age at blood sampling on the sensitivity of diagnostic tests

Diagnostic method (outcome Variable)	P value (OR [95% CI]) for covariateb
	Treatment	Trimester of maternal infection	Male gender	Newborn age
IgM ISAGA (n = 144)	0.000 (0.117 [0.041–0.333])	0.001 (3.417 [1.648–7.085])	0.021 (2.680 [1.160–6.192])	0.104
IgM WB (n = 69)	0.002 (0.049 [0.007–0.322])	0.000 (6.623 [2.461–17.874])	0.003 (0.174 [0.055–0.547])	0.292
IgG WB (n = 70)	0.005 (0.115 [0.025–0.518])	0.007 (2.931 [1.348–6.372])	ND	0.242
qPCRa (n = 80)	0.480 (0.292 [0.068–0.990])	ND	ND	0.007 (1.091 [1.024–1.162])

^aBlood or CSF.

^bND, not determined because the P value in univariate analysis was <0.2 (results not shown).