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. Author manuscript; available in PMC: 2022 Jan 15.
Published in final edited form as: Arch Biochem Biophys. 2020 Dec 1;697:108702. doi: 10.1016/j.abb.2020.108702

Figure 2. Overview of kynurenine pathway.

Figure 2.

IDO, indole- 2,3-dioxygenase; TDO, tryptophan-2,3- dioxygenase; AFMID, Arylformamidase; KAT, kynurenine aminotransferase; KYNU, kynurenase; HD, Huntington’s disease; PD, Parkinson’s disease; AD, Alzheimer’s disease; SCZ, Schizophrenia. Neurotoxic metabolites 3-hydroxykynurenine and quinolinic acid are highlighted in red. Neuroprotective kynurenic acid is highlighted in green. Their relation with neuro disorders is labelled in the figure.