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. 2021 Apr 27;9:667800. doi: 10.3389/fcell.2021.667800

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Copyright © 2021 Liu, Han, Hu, Cai, Yang, Ren, Zhao, Lu, Zhou and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Targets prediction and functional enrichment analysis of DEMs. (A) MiRNA–mRNA interaction network based on the hot miRNAs. (B) Target gene expression in DLBCL from the GEPIA database (normal = 337, DLBCL = 47). (C–F) Visualization of GO enrichment analysis (C–E) and KEGG pathway enrichment analysis (F) of 484 target genes of DEMs. The Y-axis stands for terms, and the X-axis represents the rich factor. The significance of the term is described by the color with red representing the highest significance. The count of the gene enrichment in the term is described by the size of the node. GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.