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. 2021 Apr 27;9:667800. doi: 10.3389/fcell.2021.667800

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Copyright © 2021 Liu, Han, Hu, Cai, Yang, Ren, Zhao, Lu, Zhou and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Enrichment analysis and regulatory networks of miR-107. (A) Venn diagram indicates 28 potential target genes of miR-107 predicted by four databases, including TargetScan, miRDB, miRTarBase, and PicTar. (B) Table of target genes of miR-107. (C) GO enrichment and KEGG analysis of target genes by DAVID. (D) Representative biomolecular network about 28 genes targeted by miR-107 and corresponding pathways against KEGG. (E) LncRNA–miRNA–mRNA network predicted by Cytoscape. Target genes of miR-107 are represented as oval-shaped nodes. LncRNAs are represented as triangle-shaped nodes. Red indicates upregulation, and green indicates downregulation. (F) Target genes upregulated in DLBCL from GEPIA database (Normal = 337, DLBCL = 47) *p < 0.05.