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. 2021 Feb 9;83(4):746–753. doi: 10.1292/jvms.21-0014

Table 2. Top 20 of biological functions of 62 up-regulated genes.

Functions annotation P-value Predicted activation state Activation z-score Number of molecules
Quantity of gonadal cells 6.20E-05 Increased 2.198 5
Fertility 2.16E-03 Increased 2.189 5
Litter size 8.56E-04 1.982 4
Quantity of germ cells 6.52E-04 1.951 4
Quantity of gonads 1.34E-05 1.864 6
Development of neurons 7.02E-05 1.761 10
Neuritogenesis 2.61E-04 1.516 8
Long-term potentiation 4.23E-04 1.4 5
Quantity of bone 4.07E-04 1.091 5
Differentiation of bone cells 4.13E-04 1.067 6
Necrosis of epithelial tissue 5.44E-03 1 6
Apoptosis of epithelial cells 5.58E-03 1 4
Quantity of ovarian follicles 1.61E-06 0.927 5
Differentiation of connective tissue cells 2.67E-04 0.713 8
Quantity of osteoclasts 1.98E-04 0.577 4
Sprouting 5.20E-03 0.44 5
Quantity of connective tissue 1.83E-04 0.13 8
Quantity of protein in blood 2.06E-03 −0.003 6
Quantity of cytokines 3.35E-04 −0.09 5
Concentration of hormone 5.18E-04 −0.095 6

Activation z-score; >2.0 or < −2.0 is significantly predictive.