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Kaplan-Meier survival curves for patients with stage IVa HNSC (n=1,033). (A) Overall survival (OS), (B) disease-free survival (DFS) treated surgically (surgery group) or nonsurgically (CRT group). HNSC, head and neck squamous cell carcinoma; Surgery group, patients treated primarily by surgery with curative intent with/without (neo)adjuvant treatment; CRT group, patients treated primarily with chemotherapy and radiotherapy. *Statistically significant (P<0.05).
