Tang 2013.
Study characteristics | ||
Methods | Study design: RCT Location: adult ICU (China) Number of centres: 1 Study period: 14 months (dates not given) Funding source: unclear |
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Participants | Setting: adult ICU Inclusion criteria: all patients admitted to the ICU with receipt of mechanical ventilation of at least 48 hours were assessed for inclusion in the study. Exclusion criteria: unclear Number randomised: 60 (gp A: 30; gp B: 30) Number evaluated: 60 (gp A: 30; gp B: 30) Baseline characteristics: age: 56 (13.22); M/F: 38/22 "Age and sex comparable between groups" |
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Interventions |
Comparison: saline rinse vs saline swab Gp A: rinse oral cavity with saline Gp B: saline swab with saline cotton ball |
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Outcomes | 1. VAP 2. Mortality 3. Duration of ventilation |
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Notes | Sample size calculation: not reported | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | No details provided |
Allocation concealment (selection bias) | Unclear risk | No details provided |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Blinding not mentioned and not possible |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Assessor blinding not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Low risk | All randomised participants included in analysis |
Selective reporting (reporting bias) | Low risk | Planned outcomes reported |
Other bias | Unclear risk | The authors did not give a detailed description about the intervention methods and frequency of oral care in each group. |