Bacitracin, 20 000 units orally, four times daily for 7 days |
Fusidic acid, 500 mg orally, three times daily for 10 days |
Teicoplanin, 100–400 mg orally, twice daily for 10 days |
Tigecycline, 100 mg intravenous loading dose, then 50 mg twice daily for 14–21 days |
Rifampicin, 300–600 mg orally, twice daily (in combination with vancomycin for relapse) for 7–10 days |
Rifaximin, 200 mg orally, three times daily for 10 days |
Nitazoxanide, 500 mg orally, twice daily for 7–10 days |
Tolevamer, 6 g orally, daily for 14 days |
Antibodies to C. difficile toxins A and B (anti-TcdA and anti-TcdB, 10 mg/kg, single dose in combination with metronidazole or vancomycin) |
Fecal enema — consider logistical issues; donor screening required |
Intravenous gammaglobulin |