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. 2021 Apr 30;12:20406207211007058. doi: 10.1177/20406207211007058

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© The Author(s), 2021

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Figure 3. — Single-option questions relating to the percentage reduction in bleeds deemed to be a clinically significant improvement. Results shown are from the Round 2 questionnaire (questions informed by numerical questions in Round 1), excluding participants who indicated they had insufficient expertise. The threshold for achieving consensus (⩾70% participants selecting the same option), is marked by the dashed horizontal line. (a) Bleeds per year (any severity). Question worded as ‘Based on your response to the previous questions, what percentage reduction in bleeds per year (any severity) on prophylaxis would you then consider to be a clinically significant improvement?’. (b) Joint bleeds per year (any severity). Question worded as ‘Based on your response to the previous question, what percentage reduction in joint bleeds per year (any severity) on prophylaxis would you then consider to be a clinically significant improvement?’. (c) Major bleeds per year (joint or muscle). Question worded as ‘Based on your response to the previous question, what percentage reduction in major bleeds per year (joint or muscle) on prophylaxis would you then consider to be a clinically significant improvement?’.