Table 1.

Question types and consensus thresholds used in questionnaires.

Question type	Definition	Example questions	Consensus threshold	Agreement threshold for rephrasing the question	Agreement threshold for restating the question
6-Point Likert scale	Assessing agreement through options from ‘1’ (strongly disagree) to ‘6’ (strongly agree).22 Agreement was defined as a participant choosing options ‘5’ or ‘6’ whilst disagreement was defined as a choice of ‘1’ or ‘2’. 6-Point scales were used to ensure participants indicated a preference towards either agreement or disagreement17	‘Joint health should be regularly measured in routine comprehensive care visits by a suitably trained physiotherapist using a validated tool’ (1 = strongly disagree; 6 = strongly agree)a	⩾70% participants agreeing/disagreeing	⩾60% but <70% participants agreeing/disagreeing	<60% participants agreeing/disagreeing
Ranking	Participants asked to rank multiple options in terms of importance from ‘1’ (most important) to ‘4’ (least important) in Round 1 or from ‘1’ (most important) to ‘3’ (least important) in Round 217	‘Please rank the following recommendations in terms of their importance when offering a further round of ITI to patients who inadequately respond to their first round of ITI at the full dose of 200 IU/kg/day (1 = most important; 3 = least important) pdFVIII alone pdFVIII and immunosuppression Immunosuppression alonea	Kendall’s W statistic (W) ⩾0.7	0.6 ⩽ W < 0.7	W < 0.6
Single-option	Participants asked to select one answer from multiple options23,24	‘What annual bleed rate do you feel justifies prophylaxis in adults?’a	⩾70% participants choosing the same option	⩾60% but <70% participants choosing the same option	<60% participants choosing the same option
Numerical	A free-text, open-ended question where participants were asked to provide a numerical response17	‘Based on your response to the previous question, what percentage reduction in joint bleeds (any severity) on prophylaxis would you then consider to be a clinically significant improvement in adults?’b	Consensus not assessedc	Responses used to inform questions in subsequent round	Responses used to inform questions in subsequent round
Free-text questions	Optional free-text, open-ended questions both in the survey, and at the end of each questionnaire section (to allow participants to provide context to their responses)17	‘How should mild/moderate haemophilia A patients with inhibitors be treated to eradicate their inhibitors?’b‘If you have any additional comments related to prophylaxis, please add them to this text box’d	Consensus not assessedc	Responses used to inform questions in subsequent round	Responses used to inform questions in subsequent round

Participants could also select DNW for any questions they did not wish to answer, and in Round 2 an IE option was also added.

^aExample question from the Round 2 questionnaire.

^bExample question from the Round 1 questionnaire.

^cResponses instead used to inform the questions in subsequent round.

^dExample question from the Round 2 questionnaire whereby participants could add additional details at the end of a questionnaire section.

DNW, do not wish to answer; IE, insufficient expertise; ITI, immune tolerance induction; IU, international units; pdFVIII, plasma-derived factor VIII.