Figure 1.

Platelet count over time in patients with an early response (platelets ⩾50,000/µL by week 12) in dark blue, patients who showed clinical benefit without an early response (platelets ⩾30,000/µL) in green, and patients with limited or no benefit (platelets <30,000/µL) in red. Shaded areas represent the 25th to 75th percentiles. Platelet counts affected by rescue therapy are not included. The number of patients contributing data at each time point is shown below the graph. Data points with ⩽5 patients are shown by a dotted line.