Table 2.

Diagnostic yield stratified by sample type and clinical syndrome of cryptococcosis in patients with diabetes mellitus.

Diagnostic test	All cases N = 47	Disseminated N = 3	Pulmonary N = 7	CNS N = 32	Cutaneous N = 1	Peritoneal N = 1	Pleural N = 1	Thyroid N = 1	Adrenal N = 1
Culture (any site)	38 (80.9)	2 (66.7)	4 (57.1)	29 (90.6)	1 (100)	1 (100)		1 (100)
Blood culture	5 (10.6)	1 (33.3)	1 (14.3)	2 (6.3)				1 (100)
CSF culture	26 (55.3)			26 (81.3)
BAL culture	1 (2.1)		1 (14.3)
Sputum culture	1 (2.1)		1 (14.3)
Urine culture	1 (2.1)			1 (3.1)
Skin and soft tissue culture	4 (8.5)	1 (33.3)	1 (14.3)		1 (100)	1 (100)
CrAg (all)	9 (19.1)	1 (33.3)	1 (14.3)	4 (12.5)		1 (100)	1 (100)		1 (100)
Serum CrAg	4 (8.5)		1 (14.3)			1 (100)	1 (100)		1 (100)
CSF CrAg	5 (10.6)	1 (33.3)		4 (12.5)		1 (100)
Histopathology	9 (19.1)	1 (33.3)	5 (71.4)	7 (21.9)				1 (100)	1 (100)

BAL, bronchoalveolar lavage; CrAg, cryptococcal antigen; CSF, cerebrospinal fluid.