Skip to main content
. 2021 May 10;181(8):1121–1123. doi: 10.1001/jamainternmed.2021.1819

Table. Demographic and Clinical Characteristics by Anticoagulant Use.

Characteristic No. (%) Adjusted OR (95% CI)
Anticoagulation in the last 6 mo of life (n = 5033) No anticoagulation in the last 6 mo of life (n = 10 184)
Age (overall), y
<80 785 (15.6) 1142 (11.2) 1 [Reference]
80 to 89 2560 (50.9) 4541 (44.6) 0.82 (0.74-0.92)
≥90 1688 (33.5) 4501 (44.2) 0.59 (0.52-0.66)
Female sex 3259 (64.8) 7125 (70.0) 0.88 (0.81-0.95)
Race/ethnicity
White 4325 (85.9) 8839 (86.8) 1 [Reference]
Black 473 (9.4) 861 (8.5) 0.97 (0.85-1.10)
Asian 77 (1.5) 173 (1.7) 0.80 (0.60-1.07)
Hispanic 101 (2.0) 208 (2.0) 0.97 (0.75-1.25)
Other/missinga 57 (1.1) 103 (1.0) 1.06 (0.75-1.50)
Non-Medicaid status 1916 (38.1) 3287 (32.3) 1.59 (1.45-1.69)
>1 y in nursing home 2154 (42.8) 2399 (23.6) 2.68 (2.48-2.89)
CHA2DS2VASC scoreb
<4 681 (13.5) 1661 (16.3) 1 [Reference]
5-6 1914 (38.0) 4242 (41.7) 1.10 (0.99-1.23)
>7 2438 (48.4) 4281 (42.0) 1.38 (1.23-1.54)
ATRIA scorec
<3 796 (15.8) 2205 (21.7) 1 [Reference]
4-6 1690 (33.6) 3584 (35.2) 1.19 (1.07-1.32)
>7 2547 (50.6) 4395 (43.2) 1.25 (1.13-1.39)
Other clinical factors
Rejection of care 454 (9.0) 844 (8.3) 1.03 (0.91-1.17)
Falls 1690 (33.6) 3214 (31.6) 1.04 (0.96-1.12)
Weight loss 1856 (37.0) 3363 (33.5) 1.09 (1.01-1.18)
Pressure ulcer 2052 (40.8) 3228 (31.7) 1.37 (1.27-1.48)
Difficulty swallowing 1136 (22.6) 2008 (19.8) 1.12 (1.02-1.22)
Restraint use 189 (3.8) 433 (4.3) 0.79 (0.66-0.95)
Hospice use 1296 (25.8) 3375 (33.1) 0.76 (0.70-0.83)

Abbreviation: OR, odds ratio.

a

Other includes American Indian, Alaskan Native, Native Hawaiian, or Pacific Islander.

b

The CHA2DS2VASC score predicts annual stroke risk among persons with atrial fibrillation using the following risk factors: congestive heart failure, hypertension, age [>65 years = 1 point; >75 years = 2 points], diabetes, previous stroke or transient ischemic attack [2 points], and vascular disease.

c

The ATRIA (Anticoagulation and Risk Factors In Atrial Fibrillation) bleeding risk score predicts annual bleeding risk among persons anticoagulated for atrial fibrillation using the following risk factors: age ≥75 years (2 points), anemia (3 points), renal disease (3 points), prior bleeding (1 point), and hypertension (1 point).