A, Correlation between serum HexNAc level and Expanded Disability Status Scale (EDSS) score in the confirmatory cohort. B, Correlation between serum HexNAc level and multiple sclerosis functional composite (MSFC) z score in the confirmatory cohort. C, Correlation between serum HexNAc level and time since diagnosis. D, Correlation between serum HexNAc level and Multiple Sclerosis Severity Scale (MSSS) score. Coefficient B, SE, dark blue regression line, and light blue area 95% CI are from uncorrected linear regression models.