Table 1.

Summary of Clinical Scales of Spinocerebellar Ataxias

Methods	Comment	Reference
International Cooperative Ataxia Rating Scale (ICARS) Scale for the assessment and rating of ataxia (SARA) Brief Ataxia Rating Scale (BARS) Neurological Examination Score for the Assessment of Spinocerebellar Ataxia (NESSCA) The Inventory of Non-Ataxia Symptoms (INAS) Composite Cerebellar Functional Severity Score (CCFS) and CCFS with writing test SCA Functional Index (SCAFI) Cerebellar Cognitive Affective Syndrome Scale (CCAS) UHDRS IV EQ-5D Patient Health Questionnaire-9 (PHQ-9)	Evaluate various body part of ataxia motor symptoms, including oculomotor examination (0–100) Most extensively used ataxia scale with only 8 domains assessment without oculomotor evaluation. (0–40) Only evaluate 5 domains, including oculomotor evaluation (0–30) Originally developed for SCA3 but later validated in SCA2. Including items to assess cerebellar ataxia neuropathy, parkinsonism, and pyramidal signs. (0–40) Evaluate extra-cerebellar symptoms associated with SCA patients. A part of the scale is subjective, patient reported outcomes. (0–16) Consisted of two performance-based tasks: nine-hole pegboard test and click test Consists of three functional measures: timed 8-meter walk, 9-hole peg test, and PATA repetition. Assess the cognition of ataxia patients Patient reported functional capacity Patient reported functional capacity and overall health A self-administered questionnaire to assess the severity of depression	[20] [21] [22] [23, 24] [28] [29] [30] [31] [38] [29] [36]