Fig. 2.

Association between von Willebrand factor collagen-binding admission level and in-hospital mortality in COVID-19 patients. a Receiver operating curves evaluating von Willebrand factor collagen-binding (VWF: CB) ability to predict in-hospital-mortality estimated by the area under the curve (AUC) value. The diagonal black-dotted segment is the reference line. b Survival curves according to VWF:CB level using a Kaplan–Meier estimator. Data are shown for patients with low VWF:CB (< 446%) and high von VWF:CB (> 446%). Survival curves are compared using the log-rank test. c Forest plot showing the Cox-proportional hazards model for VWF:CB adjusted for age, body mass index (BMI), D-dimer, and C-reactive protein (CRP). For each variable, black squares represent hazard ratios (HR) and solid black lines represent HR 95% confidence intervals