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. 2019 Mar 28;89(5):804–811. doi: 10.2319/072418-536.1

Figure 3.

Figure 3.

Blockade of FOXM1 increases the RANKL/OPG ratio in human PDLCs. (A,B) The protein and mRNA levels of RANKL and OPG in PDLCs treated with increasing dosage of Siomycin A were determined by Western blotting (A) and qRT-PCR (B), respectively. GAPDH served as a loading control. (C) PDLCs were transfected with siRNA against FOXM1 (siFOXM1) or the none-sense control (siNC). The mRNA levels of indicated genes were determined by qRT-PCR. Data represent the mean ± SD for triplicate experiments. *P < .05.