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. 2019 Mar 28;89(5):804–811. doi: 10.2319/072418-536.1

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Figure 4. — Influence of FOXM1 inhibition on the proliferation and osteogenic differentiation potential of PDLCs. (A) Human PDLCs were transfected with siRNA against FOXM1 (siFOXM1) or none-sense control (siNC; left panel) or pretreated with increasing dosage of Siomycin A (right panel). Then, cells were induced toward osteogenic differentiation and subjected to ALP staining (left panel) or ALP activity assay (right panel). Data represent mean ± SD for triplicate experiments. *P < .05. (B) PDLCs were cultured in medium containing indicated concentrations of Siomycin A for 2 weeks. Results of the crystal violet staining are shown.