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. 2021 May 11;19(9):1845–1854.e6. doi: 10.1016/j.cgh.2021.05.011

Table 3.

Odds of Infection With Severe Acute Respiratory Syndrome Coronavirus 2 for Cases Compared With Controls According to Current, Former, or Never Use of Proton Pump Inhibitors

Proton pump inhibitor use Crude odds ratio (95% CI) Adjusteda odds ratio (95% CI)
Current versus never 1.04 (1.00–1.08) 1.08 (1.03–1.13)
Current low dose versus never 1.01 (0.95–1.07) 1.04 (0.98–1.11)
Current high dose versus never 1.06 (1.01–1.11) 1.11 (1.05–1.16)
Current versus former 0.98 (0.93–1.02) 1.00 (0.95–1.05)
Former versus never 1.08 (1.06–1.10) 1.08 (1.06–1.10)

CI, confidence interval.

a

Adjusted for age, sex, comorbidities, current medication use, Charlson Comorbidity Index, and number of hospital admissions within the last 3 years.