Table 1.
Classification of disease type families and affected children
| Type of MLD | |||||
|---|---|---|---|---|---|
| Late-infantile (< 2½ years at onset) | Juvenile (2½ to 16 years at onset) | Adult (> 16 years at onset) | PCH2 | Total | |
| Families (n) | 8 | 18 | 1 | 16 | 43 |
| Mothers (n) | 8 | 16 | 1 | 16 | 41 |
| single mothers (n) | 1 | 3 | 0 | 1 | 5 |
| Fathers (n) | 7 | 14 | 1 | 13 | 35 |
| Children (n) | 8 | 21 | 1 | 19 | 49 (25♀/24♂) |
| age in yrs. at time of surveya |
5.8 (3.1–8.4) |
19.1 (3.2–41.4) |
31.1 (31.1–31.1) |
9.9 (0.8–20.0) |
11.6 (0.8–41.4) |
aMedian age (range)
MLD, metachromatic leukodystrophy; PCH2, pontocerebellar hypoplasia type 2