Table 1.
clinical characteristics in MetS and non-MetS patients with poor and good collateralization
| Variables | Overall | MetS | non-MetS | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Poor collateralization n = 355 | Good collateralization n = 1298 | P value | Poor collateralization n = 222 | Good collateralization n = 640 | P value | Poor collateralization n = 133 | Good collateralization n = 658 | P value | |
| Male, n(%) | 294 (82.8) | 1074 (82.7) | 0.974 | 174 (78.4) | 508 (79.4) | 0.753 | 120 (90.2) | 566 (86.0) | 0.192 |
| Age, years | 57.7 ± 10.5 | 59.1 ± 10.3 | 0.022 | 57.2 ± 10.6 | 58.7 ± 10.2 | 0.057 | 58.6 ± 10.4 | 59.6 ± 10.3 | 0.346 |
| BMI, Kg/m2 | 28.1 ± 3.7 | 26.0 ± 3.1 | < 0.001 | 28.9 ± 4.0 | 26.9 ± 3.1 | < 0.001 | 26.9 ± 2.8 | 25.2 ± 2.8 | < 0.001 |
| HT, n(%) | 255 (71.8) | 816 (62.9) | 0.002 | 182 (82.0) | 497 (77.7) | 0.174 | 73 (54.9) | 319 (48.5) | 0.178 |
| T2DM, n(%) | 156 (43.9) | 414 (31.9) | < 0.001 | 118 (53.2) | 285 (44.5) | 0.027 | 38 (28.6) | 129 (19.6) | 0.021 |
| Renal disease, n(%) | 10 (2.8) | 25 (1.9) | 0.302 | 8 (3.6) | 13 (2.0) | 0.190 | 2 (1.5) | 12 (1.8) | 0.799 |
| Metabolic syndrome, n(%) | 222 (62.5) | 640 (49.3) | < 0.001 | – | – | – | – | – | – |
| Former smoker, n(%) | 56 (15.8) | 211 (16.3) | 0.827 | 32 (14.4) | 98 (15.3) | 0.747 | 24 (18.0) | 113 (17.2) | 0.809 |
| Current smoker, n(%) | 146 (41.1) | 540 (41.6) | 0.872 | 80 (36.0) | 267 (41.7) | 0.137 | 66 (49.6) | 273 (41.5) | 0.197 |
| Prior MI, n(%) | 102 (28.7) | 359 (27.7) | 0.689 | 63 (28.4) | 189 (29.5) | 0.745 | 39 (29.3) | 170 (25.8) | 0.405 |
| Stroke, n(%) | 20 (5.6) | 89 (6.9) | 0.411 | 14 (6.3) | 49 (7.7) | 0.505 | 6 (4.5) | 40 (6.1) | 0.481 |
| History of PCI, n(%) | 103 (29.0) | 386 (29.7) | 0.791 | 69 (31.1) | 211 (33.0) | 0.605 | 34 (25.6) | 175 (26.6) | 0.806 |
| SBP, mmHg | 132.6 ± 16.1 | 127.3 ± 16.1 | < 0.001 | 135.1 ± 15.5 | 128.6 ± 16.3 | < 0.001 | 128.3 ± 16.4 | 126.0 ± 15.7 | 0.117 |
| DBP, mmHg | 79.5 ± 11.8 | 75.7 ± 10.6 | < 0.001 | 81.0 ± 12.0 | 76.3 ± 10.6 | < 0.001 | 77.2 ± 11.0 | 75.0 ± 10.5 | 0.033 |
| HR, bpm | 71.7 ± 9.4 | 72.0 ± 10.5 | 0.558 | 71.8 ± 9.4 | 72.7 ± 10.5 | 0.309 | 71.4 ± 9.3 | 71.4 ± 10.5 | 0.967 |
| FBG, mmol/L | 6.2 (5.1, 8.1) | 5.7 (5.1, 7.2) | < 0.001 | 6.9 (5.6, 8.1) | 6.4 (5.5, 8.1) | 0.033 | 5.4 (4.9, 6.4) | 5.3 (4.9, 5.9) | 0.163 |
| TG, mmol/L | 1.6 (1.2,2.4) | 1.4 (1.0,2.0) | < 0.001 | 2.0 (1.6, 2.8) | 1.9 (1.3, 2.5) | 0.002 | 1.2 (1.1, 1.6) | 1.1 (0.9, 1.4) | < 0.001 |
| TC, mmol/L | 4.1 ± 1.3 | 3.8 ± 1.0 | 0.001 | 4.1 ± 1.5 | 3.8 ± 1.1 | 0.004 | 4.0 ± 1.0 | 3.8 ± 1.0 | 0.109 |
| LDL-C, mmol/L | 2.3 ± 1.0 | 2.2 ± 0.9 | 0.189 | 2.3 ± 1.1 | 2.2 ± 0.9 | 0.319 | 2.4 ± 0.9 | 2.3 ± 0.9 | 0.257 |
| HDL-C, mmol/L | 1.0 (0.8, 1.2) | 1.0 (0.9, 1.2) | 0.007 | 0.9 (0.8, 1.0) | 0.9(0.8, 1.0) | 0.545 | 1.1(0.9, 1.2) | 1.1(1.0, 1.3) | 0.489 |
| WBC, 1012/L | 7.1 ± 1.8 | 7.0 ± 1.8 | 0.179 | 7.0 ± 1.8 | 7.1 ± 1.8 | 0.526 | 7.2 ± 1.8 | 6.8 ± 1.8 | 0.052 |
| HGB, g/L | 144 (133,153) | 142 (132,152) | 0.149 | 143 (133, 154) | 142 (132, 152) | 0.293 | 144 (134,152) | 142 (132, 152) | 0.345 |
| PLT, 109/L | 217.2 ± 54.5 | 218.4 ± 57.0 | 0.719 | 219.0 ± 54.8 | 219.4 ± 57.0 | 0.803 | 214.1 ± 54.1 | 217.4 ± 57.1 | 0.546 |
| Cr, μmol/L | 78.5 ± 21.5 | 77.0 ± 33.1 | 0.418 | 79.3 ± 23.7 | 77.9 ± 31.4 | 0.562 | 77.3 ± 17.2 | 76.1 ± 34.6 | 0.712 |
| UA, μmol/L | 361.2 (310.9, 418.2) | 350.7 (299.2, 419.0) | 0.186 | 364.1 (311.0, 425.3) | 363.6 (307.5, 432.7) | 0.778 | 357.5 (309.2, 410.9) | 341.1 (291.3, 406.1) | 0.072 |
| eGFR, mL/(min·1.73 m2) | 92.8 ± 17.5 | 93.3 ± 17.0 | 0.657 | 92.0 ± 18.9 | 92.6 ± 17.8 | 0.676 | 94.3 ± 14.8 | 94.0 ± 16.1 | 0.834 |
| HCY, μmol/L | 16.2 ± 8.9 | 16.2 ± 10.0 | 0.930 | 15.7 ± 8.1 | 15.8 ± 9.6 | 0.878 | 17.0 ± 10.1 | 16.6 ± 10.3 | 0.715 |
| GA, % | 15.3 (13.8, 17.8) | 14.5 (13.3, 16.6) | < 0.001 | 15.6 (14.0, 18.0) | 14.9 (13.4,18.3) | 0.023 | 14.7 (13.5, 16.7) | 14.2 (13.3, 15.8) | 0.039 |
| LVEF, % | 56.9 ± 7.8 | 56.1 ± 7.8 | 0.134 | 57.0 ± 7.2 | 56.6 ± 7.7 | 0.513 | 56.8 ± 8.6 | 55.8 ± 7.9 | 0.212 |
| LVEDd, mm | 50.6 ± 5.2 | 51.0 ± 5.2 | 0.249 | 50.1 ± 5.0 | 50.8 ± 5.2 | 0.084 | 51.5 ± 5.5 | 51.2 ± 5.2 | 0.502 |
| LVEDs, mm | 35.3 ± 6.0 | 35.8 ± 5.8 | 0.164 | 35.0 ± 5.4 | 35.5 ± 5.7 | 0.254 | 35.8 ± 6.8 | 36.1 ± 5.8 | 0.644 |
| Medication, n (%) | |||||||||
| Antiplatelet | 355 (100) | 1298 (100) | 1 | 222 (100) | 640 (100) | 1 | 133 (100) | 658 (100) | 1 |
| Statins | 355 (100) | 1298 (100) | 1 | 222 (100) | 640 (100) | 1 | 133 (100) | 658 (100) | 1 |
| Diuretics | 45 (12.4) | 158 (12.2) | 0.798 | 33 (14.9) | 84 (13.1) | 0.514 | 12 (9.0) | 74 (11.2) | 0.452 |
| ACE inhibitors/ARBs | 150 (42.3) | 471 (36.3) | 0.040 | 107 (48.2) | 276 (43.1) | 0.190 | 43 (32.3) | 195 (29.6) | 0.536 |
| β-blockers | 236 (66.5) | 846 (65.2) | 0.648 | 148 (66.7) | 446 (69.7) | 0.402 | 88 (66.2) | 400 (60.8) | 0.245 |
| CCBs | 111 (31.3) | 369 (28.4) | 0.296 | 71 (31.3) | 221 (34.6) | 0.489 | 40 (30.1) | 148 (22.5) | 0.061 |
| Hypoglycaemic agents | 107 (30.1) | 320 (24.7) | 0.036 | 83 (37.4) | 216 (33.8) | 0.327 | 24 (18.0) | 104 (15.3) | 0.522 |
| Target vessel, n (%) | |||||||||
| RCA | 167 (47.0) | 576 (44.4) | 0.371 | 104 (46.8) | 288 (45.0) | 0.634 | 63 (47.4) | 288 (43.8) | 0.446 |
| LAD | 132 (37.2) | 491 (37.8) | 0.824 | 89 (40.1) | 227 (35.5) | 0.218 | 43 (32.3) | 264 (40.1) | 0.093 |
| LCX | 63 (17.7) | 240 (18.5) | 0.748 | 33 (14.9) | 130 (20.3) | 0.074 | 30 (22.6) | 110 (16.7) | 0.109 |
| Elevated BMI, n (%) | 88 (24.8) | 136 (10.5) | < 0.001 | 83 (37.4) | 117 (18.3) | < 0.001 | 5 (3.8) | 19 (2.9) | 0.593 |
| Elevated BP,n (%) | 293 (82.5) | 957 (73.7) | 0.001 | 208 (97.3) | 559 (87.3) | 0.009 | 85 (63.9) | 398 (60.5) | 0.460 |
| Elevated FBG, n (%) | 238 (67.0) | 751 (57.9) | 0.002 | 181 (81.5) | 516 (80.6) | 0.767 | 57 (42.9) | 235 (35.7) | 0.119 |
| Reduced HDL-C, n (%) | 247 (69.6) | 837 (64.5) | 0.073 | 195 (87.8) | 580 (90.6) | 0.235 | 52 (39.1) | 257 (39.1) | 0.993 |
| Elevated TG, n (%) | 166 (46.8) | 447 (34.4) | < 0.001 | 147 (66.2) | 376 (58.8) | 0.050 | 19 (14.3) |
71 (10.8) |
0.247 |
BMI body mass index, HT Hypertension, T2DM type 2 diabetes mellitus, Prior MI Prior myocardial infarction, History of PCI history of percutaneous coronary intervention, History of CABG history of coronary artery bypass grafting, SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, FBG Fasting blood glucose, TG Triglycerides, TC Total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, WBC white blood cell, HGB hemoglobin, PLT Platelet, Cr creatinine, UA Uric acid, HCY Homocysteine, GA Glycated albumin, LVEF ventricular ejection fraction, LVEDd left ventricular end-diastolic dimension, LVEDsleft ventricular end-systolic dimension, ACE inhibitors/ARBs Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers, CCBs calcium channel blockers, RCA Right coronary artery, LAD Left anterior descending, LCX left circumflex coronary artery