Table 1.
Top 25 DE genes in placenta of OXY females vs. CTL females. Bolded and shaded genes are also considered hub genes.
| Gene ID | Gene Name | Fold change |
P value | Expression in OXY Females |
|---|---|---|---|---|
| Prl7b1 | prolactin family 7, subfamily b, member 1 (Prl7b1) | 3.015145 | 0.000305 | ↑ |
| Ipp | IAP promoted placental gene (Ipp) | 2.04192 | 0.000411 | ↑ |
| Prl8a6 | prolactin family 8, subfamily a, member 6 (Prl8a6) | 1.900212 | 0.000452 | ↑ |
| Prl8a8 | prolactin family 8, subfamily a, member 81 (Prl8a8) | 2.190423 | 0.00071 | ↑ |
| Psg-ps1 | pregnancy specific glycoprotein pseudogene 1 (Psg-ps1) | 1.575866 | 0.002067 | ↑ |
| Ceacam12 | carcinoembryonic antigen-related cell adhesion molecule 12 (Ceacam12) | 2.148957 | 0.00272 | ↑ |
| Prl7a2 | prolactin family 7, subfamily a, member 2 (Prl7a2) | 2.344508 | 0.003038 | ↑ |
| Rgs5 | regulator of G-protein signaling 5 (Rgs5) | 1.577403 | 0.00343 | ↑ |
| Creg1 | cellular repressor of E1A-stimulated genes 1 (Creg1) | 1.669612 | 0.003814 | ↑ |
| S100a8 | S100 calcium binding protein A8 (calgranulin A) (S100a8) | 3.434036 | 0.004753 | ↑ |
| Ceacam14 | carcinoembryonic antigen-related cell adhesion molecule 14 (Ceacam14) | 1.746187 | 0.007763 | ↑ |
| Prl7c1 | prolactin family 7, subfamily c, member 1 (Prl7c1) | 1.983514 | 0.008284 | ↑ |
| Tpbpb | trophoblast specific protein beta (Tpbpb) | 1.867087 | 0.008407 | ↑ |
| Prl8a9 | prolactin family8, subfamily a, member 9 (Prl8a9) | 1.57127 | 0.012147 | ↑ |
| Ceacam13 | carcinoembryonic antigen-related cell adhesion molecule 13 (Ceacam13) | 1.653706 | 0.012975 | ↑ |
| Igfbp7 | insulin-like growth factor binding protein 7 (Igfbp7) | 1.412147 | 0.014668 | ↑ |
| Ctsq | cathepsin Q (Ctsq) | 1.638126 | 0.014715 | ↑ |
| Ceacam11 | carcinoembryonic antigen-related cell adhesion molecule 11 (Ceacam11) | 1.740848 | 0.014965 | ↑ |
| Gpx3 | glutathione peroxidase 3 (Gpx3) | 1.677336 | 0.01554 | ↑ |
| Tpbpa | trophoblast specific protein alpha (Tpbpa) | 1.785004 | 0.015593 | ↑ |
| Far1 | fatty acyl CoA reductase 1 (Far1) | 1.300561 | 0.016593 | ↑ |
| Prl2c1 | prolactin family 2, subfamily c, member 1 (Prl2c1) | 1.816418 | 0.01796 | ↑ |
| Igsf8 | immunoglobulin superfamily, member 8 (Igsf8) | 0.805401 | 0.019183 | ↓ |
| Ctsk | cathepsin K (Ctsk) | 2.442033 | 0.019817 | ↑ |
| Fabp4 | fatty acid binding protein 4, adipocyte (Fabp4) | 2.105421 | 0.019899 | ↑ |