Table 1.
Parameter | No. of points (criteria for scoring) |
---|---|
Known underlying immunosuppression* | 0 (no) or 18 (yes) |
Temperature (°C) | 0 (<38.4), 33 (38.4–39.4) or 49 (>39.4) |
Organomegaly | 0 (no), 23 (hepatomegaly or splenomegaly) or 38 (hepatomegaly and splenomegaly) |
No. of cytopenias** | 0 (1 lineage), 24 (2 lineages) or 34 (3 lineages) |
Ferritin (ng/ml) | 0 (<2000), 35 (2000–6000) or 50 (>6000) |
Triglyceride (mmol/l) | 0 (<1.5), 44 (1.5–4) or 64 (>4) |
Fibrinogen (mg/l) | 0 (>2.5) or 30 (≤2.5) |
Serum glutamic oxaloacetic transaminase (IU/l) | 0 (<30) or 19 (≥30) |
Haemophagocytosis features on bone marrow aspirate | 0 (no) or 35 (yes) |
Human immunodeficiency virus positive or receiving long-term immunosuppressive therapy (i.e., glucocorticoids, cyclosporine, azathioprine).
Defined as a haemoglobin level of ≤9.2 mg/dl and/or a leucocyte count of ≤5000/mm3 and/or a platelet count of ≤10,000/mm3