Figure 3.

MAPK14 expression level is increased in serum and CD14⁺PBMCs from patients with OP.(A) MAPK14 expression was higher in patients with postmenopausal OP compared with healthy volunteers. (B) Negative correlation between miR-22-3p and MAPK14 expression. (C) MAPK14 expression was increased in CD14⁺PBMCs treated with M-CSF and RANKL for 6 days compared with untreated cells. ^**P<0.01. OP, osteoporosis; miR, microRNA; PBMCs, peripheral blood mononuclear cells; M-CSF, macrophage colony stimulating factor; RANKL, receptor activator of nuclear factor-κB ligand.