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. 2021 May 2;22(1):692. doi: 10.3892/etm.2021.10124

Figure 4.

Figure 4

miR-22-3p mimic inhibits CD14+PBMC proliferation by targeting MAPK14. (A-C) pcDNA3.1-MAPK14 was successfully transfected in CD14+PBMCs. (D) pcDNA3.1-MAPK14 reversed the effects of miR-22-3p mimic on CD14+PBMCs proliferation. **P<0.01 vs. pcDNA3.1 or miR-NC mimic + pcDNA3.1. &P<0.05 vs. miR-22-3p mimic + pcDNA3.1. OP, osteoporosis; miR, microRNA; PBMCs, peripheral blood mononuclear cells; M-CSF, macrophage colony stimulating factor; RANKL, receptor activator of nuclear factor-κB ligand; NC, negative control.