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. 2021 Apr 22;22(1):666. doi: 10.3892/etm.2021.10098

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Copyright: © Song et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of LRRC17 expression on osteogenic and adipogenic differentiation of INFH-hBMSCs. (A and B) Changes in LRRC17, BMP2, OPG, CEBPα, PPARγ mRNA and protein expression after the overexpression and interference with LRRC17. ^*P<0.05, ^**P<0.01 vs. respective control. hBMSCs, human bone marrow mesenchymal stem cells; INFH, idiopathic necrosis of the femoral head; LRRC17, leucine-rich repeat-containing 17; OPG, osteoprotegerin; BMP2, bone morphogenetic protein 2; PPARγ, peroxisome proliferator-activated receptor γ; CEBPα, CCAAT/enhancer-binding protein α; sh-, short hairpin RNA; con-, control.