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. 2021 Apr 22;22(1):664. doi: 10.3892/etm.2021.10096

Figure 2.

Figure 2

BAG5 is a target gene of miR-770-5p. (A) TargetScan was used to predict the binding sites between BAG5 and miR-770-5p. (B) Transfection efficiency of miR-770-5p mimic. (C) Dual luciferase reporter assays were performed to verify the interaction between BAG5 and miR-770-5p. (D) Reverse transcription-quantitative PCR was performed to detect BAG5 expression levels in the peripheral blood of patients with T2DM and healthy volunteers. **P<0.01 vs. mimic control; ##P<0.01 vs. healthy. BAG5, Bcl-2 associated athanogene 5; miR, microRNA; T2DM, type 2 diabetes mellitus; WT, wild-type; MUT, mutant; UTR, untranslated region.