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Effect of exposure of hyper IL-6 on the level of expression of Sp1 protein in pancreatic acinar cell line PAC 266-6 (A) and mouse PACs (B). PACs were exposed to hyper IL-6 (100 ng/mL) for 24 h, and the level of Sp1 protein expression was determined by Western blot (inset). Data are means ± SE of 3 independent experiments. *P < 0.05.
