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. 2020 Nov 4;320(1):G108–G116. doi: 10.1152/ajpgi.00361.2020

Fig. 7.

Fig. 7.

Role of Stat3 signaling pathway in mediating the effect of hyper IL-6 on thiamin uptake in the pancreatic acinar cell line PAC 266-6. A: activation of Stat3 in PAC 266-6 exposed to hyper IL-6 (100 ng/mL) and pretreated with 50 µM S3I-201 (a Stat3 inhibitor). Inset: representative Western image for phospho-Stat3 and total-Stat3. B: carrier-mediated thiamin uptake was examined in PAC 266-6 that were pretreated with S3I-201 for 1 h before hyper IL-6 treatment. Data are means ± SE of 3 independent experiments. *P < 0.05; NS, not significant.