Table 2.

List of diseases enriched with differentially expressed genes of mouse brain and heart vasculomes.

Concept ID	Disease	Aging		Hypertension		Diabetes		All
		DEG	p	DEG	p	DEG	p	DEG	p
Brain-related diseases
C0006105	Brain abscess	1	0.309	2	0.029	4	0.001	7	0.000
C3888102	Frontotemporal dementia with motor neuron disease	2	0.012	1	0.044	1	0.055	4	0.001
C0234379	Resting Tremor	4	0.001	2	0.022	2	0.031	6	0.001
C3160718	Parkinson disease	16	0.006	11	0.01	8	0.196	31	0.001
C3279222	Cerebellar hypoplasia and atrophy	10	0.000	1	0.656	5	0.035	14	0.003
C4024946	Focal white matter lesions	2	0.005	0	0.255	2	0.002	3	0.003
C0752156	Dural arteriovenous fistula	1	0.064	0	0.255	2	0.002	3	0.003
C0085200	Lewy bodies	2	0.005	2	0.001	1	0.035	3	0.003
C0151699	Intracranial hemorrhages	6	0.088	5	0.035	7	0.006	15	0.004
C3714756	Intellectual disability	152	0.000	64	0.675	71	0.769	264	0.005
C0007766	Intracranial aneurysm	9	0.356	8	0.094	13	0.003	28	0.005
C0751003	Brain aneurysm	2	0.070	0	0.484	3	0.004	5	0.008
C0086543	Cataract	42	0.102	30	0.043	26	0.416	94	0.009
C0751837	Gait ataxia	12	0.014	8	0.025	4	0.539	22	0.010
C1290398	Cerebral arterial aneurysm	6	0.455	5	0.215	12	0.000	21	0.010
C0025362	Mental retardation	115	0.000	50	0.616	54	0.772	200	0.030
Heart-related diseases
C0027051	Myocardial Infarction	31	0.001	48	0.003	47	0.003	114	0.000
C0007222	Cardiovascular Diseases	31	0.001	45	0.009	49	0.001	112	0.000
C0010054	Coronary arteriosclerosis	25	0.029	49	0.001	48	0.001	109	0.000
C0011849	Diabetes mellitus	45	0.020	83	0.001	80	0.002	190	0.000
C0003850	Arteriosclerosis	45	0.000	64	0.003	52	0.124	146	0.000
C0020538	Hypertensive disease	43	0.001	70	0.001	54	0.130	151	0.000
C1301700	Cardiovascular morbidity	2	0.019	3	0.018	3	0.017	8	0.000
C0018801	Heart failure	27	0.011	52	0.000	33	0.312	103	0.000