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. 2021 Apr 27;11:665736. doi: 10.3389/fonc.2021.665736

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Copyright © 2021 Lucchini, Merlo, Ballerini, Porcari, Sinagra, Pagnan, Rensi, Romano, Bussani, Ballotta and Zaja

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Decrease in cardiac wall thickness after chemotherapy at echocardiographic evaluation (from A to F). (A, C) interventricular septum (IVS) and posterior wall (PW) thickness, 18 mm and 15 mm respectively, from parasternal long-axis and short-axis view, before chemotherapy. (B, D) IVS and PW thickness, 12 mm and 10 mm, respectively, from parasternal long-axis and short-axis view, after chemotherapy. (E, F) right ventricular lateral wall (RV-LW) thickness, 9 mm and 6 mm, respectively, from 4 chamber view; of note, pericardial effusion decreases from 18 mm to 6 mm after chemotherapy. (G) monoclonal IgM/K before starting treatment. (H) no more detectable monoclonal paraprotein after treatment. (I) histologic sample of endomyocardial biopsy, hematoxylin-eosin staining.