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. 2021 Apr 13;11:614024. doi: 10.3389/fphar.2020.614024

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Copyright © 2021 Wang, Peng, An, Shang, Xiao, He, Chen, Zhang, Wang, Wang, Zhang, Gao, Zhu and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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XBJ and C0127s regulated infection and inflammation related signaling in septic shock. (A,B) GO analysis of the top 30 functions impacted by XBJ and C0127s. BP, biological process, CC, cellular component, MF, molecular function. Padj: P value adjusted. (C,D) The KEGG 676 analysis of top 20 pathways of the 952 genes impacted by XBJ and C0127s for >2 fold. The pathways/functions were ranked from left to right by −log (P value adjusted). (E,F) KEGG analysis of the top signaling pathways up-regulated (E) or down-regulated (F) by XBJ and C0127s were presented.