Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 13;11:614024. doi: 10.3389/fphar.2020.614024

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Wang, Peng, An, Shang, Xiao, He, Chen, Zhang, Wang, Wang, Zhang, Gao, Zhu and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

XBJ and C0127s down-regulated the mRNA expression of pro-inflammatory cytokines and cytokine receptors in the cardiac tissue after systemic infection. (A) Heat map of the gene expression influenced by XBJ, C0127, and C0127-2 in Cytokine-cytokine receptor interaction in the RNA-seq assay. (B–D) The expression of pro-inflammatory cytokines, IL-6, IL-1α, and IL-1β were detected in the cardiac tissue of different groups of mice. B. IL-6; C. IL-1α; D. IL-1β. (E–G) The expression of pro-inflammatory cytokines in the cardiac tissue of different groups of mice was determined by Real-time PCR. E. IL-6; F. IL-1α; G. IL-1β. n = 4-5/group. Results were presented as mean ± SEM (n = 4-5/group). #p < 0.05, ##p < 0.01, ###p < 0.001 vs. Sham group, *p < 0.05, **p < 0.01, ***p < 0.001 vs. CLP group.