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. 2021 Apr 13;11:614024. doi: 10.3389/fphar.2020.614024

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Copyright © 2021 Wang, Peng, An, Shang, Xiao, He, Chen, Zhang, Wang, Wang, Zhang, Gao, Zhu and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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XBJ and C0127s down-regulated the protein expression of pro-inflammatory cytokines/chemokines in the septic mice. (A,B) The serum levels of (A) IL-1β and (B) IL-6 were measured by ELISA. Each bar was represented as mean ± SEM (n = 5); (D,E) The levels of (D) IL-1β and (E) IL-6 in heart tissues were measured by ELISA. Each bar was represented as mean ± SEM (n = 5); (C,F) The expression of CXCL2 in the heart tissue of different groups was determined by western blot. Each bar was represented as mean ± SEM (n = 5/group). #p < 0.05, ##p < 0.01, ###p < 0.001 vs. Sham group, *p < 0.05, **p < 0.01, ***p < 0.001 vs. CLP group. Experiments were repeated for three times.