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. 2021 Apr 27;12:660532. doi: 10.3389/fendo.2021.660532

Figure 1.

Figure 1

Direct functional importance of imprinted genes in pancreatic beta cells falls into two major categories: modulators of beta cell mass (via changes in cellular proliferation, apoptosis and/or differentiation) and alterations to specific components of the insulin secretory apparatus. Arrowheads and blocked lines represent stimulatory and inhibitory actions on these cellular pathways, respectively.