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. 2021 May 10;9(5):e001942. doi: 10.1136/jitc-2020-001942

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

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Effect of the copy number variation (CNV) risk score on overall survival after combination therapy of programmed cell death protein 1 (PD-1) inhibitor with lenvatinib, by clinical characteristics. Forest plot for overall survival in subgroups. Estimates are based on a Cox proportional hazards model. AFP, alpha-fetoprotein; ECOG, Eastern Cooperative Oncology Group; PD-L1, programmed death-ligand 1; TBS, tumor burden score; TNM, tumor, node, metastases.