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. Author manuscript; available in PMC: 2022 May 28.
Published in final edited form as: Cancer Lett. 2021 Feb 25;506:142–151. doi: 10.1016/j.canlet.2021.01.020

Fig. 3. Confined-migrating cells express significant increased drug efflux proteins.

Fig. 3.

A-C. Quantitative comparison of drug efflux proteins (ABCG2, MDR1 and NUP62) between G55 confined-migrating cells (indicated by M) and 2D cells (indicated by C). D-E. Quantitative comparison of drug efflux proteins (ABCG2 and MDR-1) in MDA-MB-231 confined-migrating cells (indicated by M) and 2D cells (indicated by C). All Western blot results were normalized by the total protein concentration. (Average + Std). All experiments were reproduced. *p<0.05. F. Representative immunostaining images of NUP62 and ABCG2 for G55 (left) and MDA-MB-231 cells in 2D culturing and after migrating through 5 × 5 μm microchannels (5R, right). Blue: DAPI; Red: NUP62; and Green: ABCG2.