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. 2021 Apr 27;12:665541. doi: 10.3389/fimmu.2021.665541

Figure 3.

Figure 3

Comparison of cell percentages of distinct NK maturation subsets within the bone marrow microenvironment of NBM, MDS, and AML cases. (A) Percentage of bone marrow CD56bright CD94hi CD16- CD57- immature NK cells in normal bone marrow (NBM, n = 30), myelodysplastic syndromes (MDS, n = 25), and acute myeloid leukemias (AML, n = 8) cases. Bars represent the mean ± SEM (*P < 0.05, ns, not significant; one-tailed unpaired t-test). (B) Percentage of bone marrow CD56dim CD94med CD16+ CD57- mature NK cells in NBM (n = 30), MDS (n = 24), and AML (n = 8) cases. Bars represent the mean ± SEM (*P < 0.05, ns, not significant; one-tailed unpaired t-test). (C) Percentage of bone marrow CD56dim CD94low CD16+ CD57+ hypermature NK cells in NBM (n = 30), MDS (n = 25), and AML (n = 8) cases. Bars represent the mean ± SEM (ns, not significant; one-way ANOVA followed by Tukey’s Multiple Comparison test).