Table 3.
Distribution of α-SMA and Shh immunoexpression levels in different histopathological subtypes of BCCs
|
Histopathological subtype of BCC |
Antigens |
||||||
|
Location |
α-SMA |
Shh |
|||||
|
Weak |
Moderate |
Strong |
Weak |
Moderate |
Strong |
||
|
Nodular |
Tumor |
132 (51.2%) |
69 (26.7%) |
57 (22.1%) |
127 (47.2%) |
86 (32.0%) |
56 (20.8%) |
|
Stroma |
221 (75.0%) |
55 (18.6%) |
19 (6.4%) |
262 (87.3%) |
36 (12.0%) |
2 (0.7%) |
|
|
Micronodular |
Tumor |
75 (59.5%) |
33 (26.2%) |
18 (14.3%) |
53 (41.4%) |
37 (28.9%) |
38 (29.7%) |
|
Stroma |
100 (71.4%) |
28 (20.0%) |
12 (8.6%) |
103 (73.6%) |
28 (20.0%) |
9 (6.4%) |
|
|
Infiltrative |
Tumor |
92 (49.5%) |
48 (25.8%) |
46 (24.7%) |
39 (22.5%) |
56 (32.4%) |
78 (45.1%) |
|
Stroma |
120 (60.0%) |
45 (22.5%) |
35 (17.5%) |
135 (67.5%) |
53 (26.5%) |
12 (6.0%) |
|
|
Superficial |
Tumor |
210 (79.5%) |
43 (16.3%) |
11 (4.2%) |
52 (23.8%) |
83 (38.1%) |
83 (38.1%) |
|
Stroma |
289 (80.3%) |
55 (15.3%) |
16 (4.4%) |
265 (73.6%) |
61 (16.9%) |
34 (9.4%) |
|
|
Mixed |
Tumor |
313 (54.7%) |
133 (23.3%) |
126 (22.0%) |
172 (30.2%) |
183 (32.2%) |
214 (37.6%) |
|
Stroma |
427 (73.6%) |
93 (16.0%) |
60 (10.4%) |
423 (72.9%) |
112 (19.3%) |
45 (7.8%) |
|
α-SMA: Alpha-smooth muscle actin; BCC: Basal cell carcinoma; Shh: Sonic hedgehog. *The shown numerical data represent the number of visual fields estimated and demonstrated either weak or moderate and strong expression of antigen