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. 2021 May 11;10:e64020. doi: 10.7554/eLife.64020

Table 1. Patients and lesions characteristics.

Abbreviations: BMI = body mass index, FCT = fibrous cap thickness, TCFA = thin-capped fibroatheroma.

Non-ruptured Ruptured p
n = 10 n = 10
Clinical characteristics
Male sex (n, %) 8 (80%) 8 (80%) 1.000
Age (years) 68 ± 7 70 ± 10 0.689
Hypertension (n, %) 10 (100%) 9 (90%) 0.305
Hyperlipidemia (n, %) 7 (70%) 6 (60%) 0.639
Nicotine use (n, %) 3 (30%) 4 (40%) 0.639
BMI (kg/m2) 33 ± 5 30 ± 7 0.230
Total cholesterol (mg/dl) 172 ± 43 165 ± 33 0.663
LDL-c (mg/dl) 106 ± 41 101 ± 32 0.724
HDL-c (mg/dl) 39 ± 6 39 ± 6 0.972
Triglycerides (mg/dl) 161 ± 62 180 ± 108 0.640
HbA1c (%) 6.1 ± 0.5 7.4 ± 1.4 0.026
hsCRP 5.0 ± 2.3 26.7 ± 46.9 0.175
Aspirine therapy (n, %) 10 (100%) 9 (90%) 0.305
Statine therapy (n, %) 6 (60%) 6 (60%) 1.000
Lesion characteristics
Minimal FCT (µm) 97 ± 15 49 ± 10 <0.001
Mean FCT (µm) 133 ± 12 94 ± 17 0.006
Maximal lipid arc (°) 110 ± 8 178 ± 39 0.001
Lipid volume arc (mm*°) 3853 ± 1294 9876 ± 3088 0.011
Presence of TCFA (n, %) 0 (0%) 7 (70%) 0.003
Presence of macrophages (n, %) 4 (40%) 6 (60%) 0.371
Presence of spotty calcifications (n, %) 7 (70%) 8 (80%) 0.527