Table 1:
Full rotavirus vaccination | Partial rotavirus vaccination | |||||
---|---|---|---|---|---|---|
Analysis | HR** | 95% CI | P value | HR** | 95% CI | P value |
Primary analysis | 0.79 | (0.57, 1.09) | 0.13 | 0.89 | (0.66, 1.19) | 0.45 |
Sensitivity analyses | ||||||
Excluding children born in states with universal rotavirus vaccination programs*** | 0.84 | (0.59, 1.20) | 0.32 | 0.91 | (0.66, 1.24) | 0.54 |
Including intussusception in only the first diagnostic position | 0.70 | (0.48, 1.03) | 0.06 | 0.93 | (0.65, 1.33) | 0.67 |
Including only children receiving at least one dose of DTaP by the age of 6 months (model uses data from children surviving intussusception-free until at least 6 months of age) | 0.70 | (0.49, 1.01) | 0.04 | 0.70 | (0.45, 1.08) | 0.10 |
Including intussusception in only the first diagnostic position and only children receiving at least one dose of DTaP by the age of 6 months (model uses data from children surviving intussusception-free until at least 6 months of age) | 0.62 | (0.41, 0.95) | 0.02 | 0.85 | (0.51, 1.41) | 0.52 |
All rotavirus models adjust for year of birth and receipt of DTaP doses and use unvaccinated children as the referent. HR=Hazard Ratio.
2007 – 2012: Alaska, Idaho, Maine, Massachusetts, New Hampshire, New Mexico, North Dakota, Oregon, Rhode Island, Vermont, Washington, Wisconsin, Wyoming; 2013 – 2014: Connecticut, Idaho, Maine, Massachusetts, New Hampshire, New Mexico, Rhode Island, South Dakota, Vermont, Washington, Wyoming; 2015 – 2016: Alaska, Connecticut, Idaho, Maine, Massachusetts, New Hampshire, New Mexico, Rhode Island, Vermont, Washington, Wyoming.