Table 2.

Selected examples of nanoparticles used in MRI biomedical applications

Author	NP	size (nm)	Applications	Imaging	Experiment model	Ref
Winter P,M	Alpha(nu)beta(3)-Gd (paramagnetic particle)	273	Imaging angiogenesis	T1	VX-2 rabbit	50
Ghaghada K,B	Liposomal gadolinium	125	Imaging placenta as blood-pool contrast	T1	SD rats	113
Vargo K,B	Her2/neu-Oleosin-30G (Micelles)	74	Imaging target cells	T2	NIH/3T3 and T6–17 cells	114
Mekuria S,L	G4.5-Gd2O3-PEG	50.4	New T1/T2 MRI contrast agent	T1, T2	RAW264.7 cells, BALB/c mice	116
Zhang Z	SPIO	70–140	Tracking GFP gene marker	T2	GFP-R3230Ac cell line	123
Frias J,C	rHDL-Gd	14–17	Imaging and characterizing atherosclerotic plaques	T1	ApoE-/- mice	129
Rahmer J	RBC encapsulated iron particles	60	Blood-pool contrast with longer life-time	T1, T2	Mouse	130
Park I,K	USPIO-PEI	100	Determining nanoparticle vehicle unpackaging for gene	T2	HeLa cells	131
Mi P	PEGMnCaP NPs	60	PH-activatable contrast in cancer	T1, T2	Mice bearing C26 and HT-29 cells	132
Keca J,M	Mn-nanotexaphyrin	100	Imaging lymph node	T1, T2	BALB/c nude mice	133
Hu J	Micelles with PTX and SPIO	15–300	Delivering drug and MRI imaging	T2	Rabbit	134
Lanza G,M	TF-biotinylated perfluocarbon-(Gd-DTPA-BOA)@(doxorubicin /paclitaxel)	250	Evaluating and quantifying drug delivery system for vascular restenosis	T1	Porcine vascular smooth muscle cells	135
Starmans L,W	FibPep-ION-Micelles	40	Detecting and imaging thrombus	T2	Mouse	136
Jin A,Y	P-selectin-MNP(iron oxide)-PBP	50	Imaging post-stroke neuroinflammation	T2	C57BL/ 6 mice	137
Lu J	Mn-SPIO micella	80	High power liver imaging contrast	T2	In vivo	138
Oishi K	TMADM-03	44	Imaging pancreatic islet graft	T1, T2	BALB/c nude mice	139
Hachani R	DHCA functioned IONP labeled hMSCs	88.2	Imaging and tracking stem cells	T2	Swiss mice	140
Wang A,Z	TCL-SPION-Apt	66.4	Imaging prostate cancer cells and chemotherapy	T1, T2	LNCaP and PC3 cell line	141
Zhang C	HBPFPE-aptamer	7.8	Detecting breast cancer	19F-MRI	Mice bearing MDA-MB-468 cells	142