Table 5.
Select nanoparticles applied in PET/SPECT examinations
Author | NP | Size (nm) | Applications | Experiment model | Imaging modality | Ref |
---|---|---|---|---|---|---|
Lee S,B | 18F-labeled DBCO-PEGylated MSN | 100–150 | Imaging tumor | Mice bearing U87MG tumor | PET | 196 |
Zern B,J | 125/124I-labeled anti-ICAM-1/PVPh-NP | 200 | Detecting pulmonary inflammation | Mice | PET | 197 |
Schluep T | 64Cu labeled IT-101 | 37 | Monitoring pharmacokinetics and tumor dynamics | Mice bearing neuro2A tumor | PET | 198 |
Pressly E,D | 64Cu labeled CANF-comb nanoparticle | 16–22 | Imaging natriuretic peptide clearance receptor in prostate cancer | Athymic mice bearing CWR22 tumor cells | PET | 202 |
Nahrendorf M | 64Cu-TNP | 20 | Imaging macrophages in inflammatory atherosclerosis | C57BL/6 mice deficient in apolipoprotein E | PET | 203 |
Ueno T | 64Cu labeled CLIO-VT680 | 20 | Detecting rejection and immunomodulation in cardiac allografts | C57BL/6 recipients of BALB/c allografts in mice | PET | 206 |
Woodard P,K | 64Cu labeled CANF-comb nanoparticle | 16–22 | Imaging atherosclerosis in artery | C57BL/6 mice deficient in apolipoprotein E | PET | 207 |
Chrastina A | 125I silver nanoparticle | 12 | Monitoring distribution of nanoparticles | BALB/C mice | SPECT | 208 |
Kim Y,H | 125I labeled cRGD-PEG-AuNP | 31 | Detecting cancer cells and imaging tumor sites | U87MG, MCF7 cells and nude mice bearing U87MG cells | SPECT | 209 |
Tseng Y,C | 111In labeled lipid/calcium/phosphate NPs | 25 | Imaging lymph node metastasis | C57BL/6 mice, nude mice and BALB/c mice bearing 4T1-Luc2-GFP cells | SPECT | 210 |
Cheng S,H | 111In-MSN labeled neural stem cells | 70 | Tracking glioblastoma | Nude mice bearing U87MG cells | SPECT | 211 |
Zhao Y | 199AuNPs(DAPTA) | 5 | Targeted imaging tumor | 4T1 TNBC mouse | SPECT | 212 |