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. Author manuscript; available in PMC: 2021 May 11.
Published in final edited form as: Nanoscale. 2019 Jan 17;11(3):799–819. doi: 10.1039/c8nr07769j

Table 5.

Select nanoparticles applied in PET/SPECT examinations

Author NP Size (nm) Applications Experiment model Imaging modality Ref
Lee S,B 18F-labeled DBCO-PEGylated MSN 100–150 Imaging tumor Mice bearing U87MG tumor PET 196
Zern B,J 125/124I-labeled anti-ICAM-1/PVPh-NP 200 Detecting pulmonary inflammation Mice PET 197
Schluep T 64Cu labeled IT-101 37 Monitoring pharmacokinetics and tumor dynamics Mice bearing neuro2A tumor PET 198
Pressly E,D 64Cu labeled CANF-comb nanoparticle 16–22 Imaging natriuretic peptide clearance receptor in prostate cancer Athymic mice bearing CWR22 tumor cells PET 202
Nahrendorf M 64Cu-TNP 20 Imaging macrophages in inflammatory atherosclerosis C57BL/6 mice deficient in apolipoprotein E PET 203
Ueno T 64Cu labeled CLIO-VT680 20 Detecting rejection and immunomodulation in cardiac allografts C57BL/6 recipients of BALB/c allografts in mice PET 206
Woodard P,K 64Cu labeled CANF-comb nanoparticle 16–22 Imaging atherosclerosis in artery C57BL/6 mice deficient in apolipoprotein E PET 207
Chrastina A 125I silver nanoparticle 12 Monitoring distribution of nanoparticles BALB/C mice SPECT 208
Kim Y,H 125I labeled cRGD-PEG-AuNP 31 Detecting cancer cells and imaging tumor sites U87MG, MCF7 cells and nude mice bearing U87MG cells SPECT 209
Tseng Y,C 111In labeled lipid/calcium/phosphate NPs 25 Imaging lymph node metastasis C57BL/6 mice, nude mice and BALB/c mice bearing 4T1-Luc2-GFP cells SPECT 210
Cheng S,H 111In-MSN labeled neural stem cells 70 Tracking glioblastoma Nude mice bearing U87MG cells SPECT 211
Zhao Y 199AuNPs(DAPTA) 5 Targeted imaging tumor 4T1 TNBC mouse SPECT 212