Figure 1.

(a) Glomerulus with features suggestive of collapsing glomerulopathy; there is segmental collapse of capillaries and increased number of epithelial cells within the Bowman space. Several epithelial cells also reveal coarse protein reabsorption granules (arrows) (periodic acid-Schiff, original magnification ×40). (b) Proximal tubules with diffuse microvesicular degeneration. The glomerulus reveals moderate expansion of the mesangium by matrix (periodic acid-Schiff, original magnification ×40). (c) The electron microscopy reveals markedly thickened glomerular basement membranes and diffuse effacement of podocyte foot processes (original magnification ×4100). (d) Proximal tubular epithelial cells show extensive vacuolization of the cytoplasm (original magnification ×1640). (e) The renal cortical tissue is negative for severe acute respiratory syndrome coronavirus 2 antigens by immunoperoxidase staining (original magnification ×20). (f) Positive control for severe acute respiratory syndrome coronavirus 2 antigens by immunoperoxidase staining. Lung tissue obtained at autopsy from a patient who died of Coronavirus Disease 2019 (original magnification ×20).