Table 1.
Demographic and clinical characteristics of 5 cases of COVID-19 linked to the P.1 variant of SARS-CoV-2.
| Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | |
|---|---|---|---|---|---|
| Age (years) | 40 | 19 | 69 | 41 | 71 |
| Sex | Female | Male | Male | Male | Female |
| Place of residence | Manaus | Manaus | Salvador | Manaus | Salvador |
| RT-PCR for SARS-CoV-2 | Detectable | Detectable | Detectable | Detectable | Detectable |
| SARS-CoV-2 sequencing | ND | ND | P.1 lineage | P.1 lineage | P.1 lineage |
| Onset of symptoms | 23/12/2020 | 27/12/2020 | 25/12/2020 | 27/12/2020 | 25/12/2020 |
| Comorbidities | None | None | SAH | None | COPD |
| Hospital admission | No | No | Yes | Yes | Yes |
| SpO2 at admission | ND | ND | 92% | 90% | 80% |
| % lung involvement on Thorax HRCT | ND | ND | 50%–75% | 50% | 50%–75% |
| d-dimer at admission (ng/mL) | ND | ND | 1054 | 1038 | 755 |
| C reactive protein at admission (mg/L) | ND | ND | 17.8 | 5.3 | 14.7 |
| ICU admission | No | No | Yes | Yes | Yes |
| Respiratory support | No | No | HFNC | HFNC | Mechanical ventilation |
| Days in ICU | 0 | 0 | 12 | 11 | 65 |
| Days in hospital | 0 | 0 | 19 | 21 | 65 |
| Outcome | Recovery | Recovery | Recovery | Recovery | Death |
ND = not done; SpO2 = oxygen saturation (breathing room air); HRCT = high resolution computed tomography; SAH = systemic arterial hypertension; COPD = chronic obstructive pulmonary disease; HFNC = high-flow nasal cannula; RT-PCR = real-time polymerase chain reaction; ICU = intensive care unit.