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Validation of DE circRNAs. (a) Four circRNAs with significantly different expression levels between the berberine-treated group and the control group in AGS cells, which were assessed via the RNA-seq approach. (b, c) RT-qPCR validation of DE circRNAs in AGS and HGC27 cells. Data are presented as means ± SEM. P value significance: 0 ≤ ∗∗∗∗ ＜ 0.0001 ≤ ∗∗∗ ＜ 0.001 ≤ ∗∗ ＜ 0.01 ≤ ∗ ＜ 0.05.
